This build should support Vista.
Well, sort of. Installed over NeroLite 22.214.171.124, and I ended up with an installer hang a couple of times, though ignoring them and letting things continue seemed to work out OK. I did get the COM surrogate stopped responding message when adding an AVI file in Nero Vision, but the burn completed and the disc plays fine in my standalone. This is despite several instances of Aero Galss turning itself on and off early in the transcoding process, but then it finally settled on "on" and things proceeded without a hitch.
The problem though, is that my start menu stopped responding. I have the start menu set to classic, and I could browse the programs and folders, but could not select any of the items. Programs couldn't be launched (though I could double click items on the desktop, or in explorer to launch them). Even logoff and shutdown could not be selected. I ended up doing the three finger salute, selecting logoff, and logging back on, which seemed to clear up the lingering issues.